FASCINATION ABOUT LDN-27219 DRUG MECHANISM OF ACTION

A single specifically fascinating compound is LDN-27219. Whilst most tTG inhibitors are designed to bind to your protein crosslinking Energetic site, LDN-27219 as a substitute binds for the nucleotide binding pocket from the enzyme though it can be in its closed-condition conformation, and stabilizes that conformation to prevent crosslinking activi